The Kennel Murder Case is a 1933 murder mystery novel written by S. S. Van Dine with fictional detective Philo Vance investigating a complex locked room mystery.A Warner Bros. film version of The Kennel Murder Case appeared in 1933. The film was directed by Michael Curtiz and starred William Powell as Philo Vance, reprising the role after appearing as Vance in three films for Paramount, and Mary Astor as Hilda Lake, the victims' niece. Many film historians (including William K. Everson, who pronounced it a "masterpiece" in the August 1984 issue of Films in Review) consider it one of the greatest screen adaptations of a Golden Age mystery novel, and rank it with the 1946 film Green for Danger.

The Kennel Murder Case was remade by Warner in 1940 as Calling Philo Vance with James Stephenson as Vance and William Clemens directing. World War II-era espionage stood in for the skulduggery of the art world in the remake.

One of the Coe brothers is found dead in his bedroom, locked from the inside, and the other brother is found the next morning dead in the downstairs closet. There is also the clue of a wounded Doberman Pinscher, a mysteriously broken piece of priceless Chinese porcelain, and a cast of suspicious family members, servants and associates. Philo Vance solves the case based on his knowledge of dog breeding, Chinese porcelain and the annals of remarkable antique crimes.